4 Chemotherapy has not been proven to increase survival after the resection of pulmonary metastasis. 4–6 Three-year survival rates after complete resection range from 30% to 42%. There is evidence that surgical resection is the treatment of choice for pulmonary metastases from soft tissue sarcoma. 2 Although pulmonary metastases most commonly arise from primary tumors in the extremities, they may arise from almost any histologic variant or primary site. Of patients with extremity sarcoma, approximately 20% will have isolated pulmonary metastatic disease at some point in the course of their disease. The lungs are the most common sites of metastatic disease. Despite progress in multimodality treatment, more than 4000 Americans will die each year of soft tissue sarcoma.
1 Sarcoma may arise virtually anywhere, but the extremity is the most common primary site. Soft tissue sarcoma is a rare neoplasm: there are approximately 6600 cases annually in the United States.
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